Grey's Anatomy is an American medical drama television series created by Shonda Rhimes. The series premiered on March 27, 2005 on ABC; since then, eight seasons have aired. The series follows the lives of interns, residents and their mentors in the fictional Seattle Grace Mercy West Hospital in Seattle, as they struggle to complete their medical training and maintain personal lives. Despite being set in Seattle, the show is primarily filmed in Los Angeles, California.
1. Dr. Meredith Grey
Resident Meredith Grey is the central protagonist of the show, and narrator of the majority of episodes. She began the series as an intern and has since progressed along her career path. Her character is defined by her romantic relationships as well as the lingering effects her mother's affair with Richard Webber has had on her life. She is best friends with Cristina Yang and following a long romance, she has married neurosurgeon Derek Shepherd.
2. Dr. Derek Shepherd
As Chief of Neurosurgery, Derek Shepherd earned the nickname McDreamy by the female staff of Seattle Grace. The lead male character, he is known for his complicated love-life. Initially he moved to Seattle from New York to get away from his adulterous ex-wife Addison Montgomery whom he discovered was having an affair with his best friend, Mark Sloan. He subsequently began a long romance with Meredith Grey which resulted in their marriage. Recently he had a somewhat antagonistic relationship with Richard Webber whom he believed wasn't governing the hospital appropriately. He took over as the Chief of Surgery after going to the hospital board about Chief Webber's drinking problem, but resigned after nearly dying from being shot.
3. Dr. Christina Yang
Skilled Resident Cristina Yang has an indomitable passion for cardiothoracic surgery, and is almost ruthless in pursuit of her desired specialty. She is best friends with Meredith Grey, and has previously been in a relationship with Preston Burke, which ended suddenly when he left Cristina on their wedding day. Since then she has entered into a relationship with Owen Hunt, whom she marries in season 7.
4. Dr. Lexie Grey
Resident and half-sister of Meredith Grey, Lexie, was in relationships with Mark, Alex, and Jackson. Known for her photographic memory, she has earned the nickname Lexipedia. Initially she had a distant, contentious relationship with Meredith, but they have since grown closer. She is often called "Little Grey" by other doctors on staff.
5. Dr. Miranda Bailey
An attending general surgeon at Seattle Grace hospital, Miranda Bailey initially gave a cold, domineering impression, earning her the nickname "The Nazi". However her attitude has since softened and she has developed a maternal role towards the residents in the hospital. She has recently undergone a divorce which led her to turn down a fellowship in pediatric surgery.
Ellen Pompeio as Dr. Meredith Grey
Patrick Dempsey as Dr. Derek Shepherd
Sandra Oh as Christina Yang
Chyler Leigh as Lexie Grey
I love medical drama such as House, E.R., Off The Map, but IMO, this one is the best medical drama I've ever seen. I hardly compute how the plot going in every season. I read on somewhere that this is will be the last season for Patrick Dempsey. Omooo...